Figure 2.
Zürich I PrP−/− behavior resembles that of a known anosmic, the AC3−/−. (a) Scatter plot showing performance of wild type strains 129, B6, and B6129 (black dots), ZI PrP−/− (open), and AC3−/− (grey) in Trial 1 of the cookie finding test. Individuals that failed to find the cookie within the test time were assigned the conservative score of 600 s, corresponding to the total test time. Black lines represent median values. (b) Trial 2 performances for the same mice. * p<0.05; ** p<0.01, Dunn's multiple comparison test. Note that values for B6129 wild types and ZI PrP−/− differ from those in Figure 1 because this test was performed under alternate experimental conditions.