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. 2009 Jun 30;45(1):37–43. doi: 10.3164/jcbn.08-262

Fig. 4.

Fig. 4

TauCl increases HO-1 expression and elevates HO activity. (A) Levels of HO-1 mRNA expressed at 12 h after exposure to varying doses of TauCl and 1 µg/ml LPS. TauCl increased HO-1 expression in a dose-dependent manner. GAPDH mRNA expression level was used to ensure equal loading (n = 5). (B) The HO-1 protein expression increased by 0.5 mM TauCl was greater than that induced by 1 µg/ml LPS. HO-1 protein expression was determined at 12 h compared to the β-actin level (n = 5). (C) TauCl increases HO activity to a greater level than LPS did. Cells were treated with 0.5 mM TauCl for 12 h and HO activity was determined by employing the bilirubin production assay (n = 3), *p<0.01 compared to control. LPS (1 µg/ml) was used as a positive control for HO-1 expression and HO activity.