Figure 5.

Results of recent prospective studies of hippocampus stimulation

a) Randomized double-blind studies of the effectivity of bilateral hippocampus stimulation in 9 patients with temporal lobe epilepsy due to uni- or bilateral hippocampal sclerosis. Follow-up time: 18 months. Observed side effects were: skin erosions requiring treatment in 3 patients 24 months after implantation (data from Velasco et al. 2007 [22])

b) Open prospective studies of the efficacy of bilateral hippocampus stimulation in 10 patients with temporal lobe epilepsy, who underwent invasive monitoring. Follow-up time: 31 months. No subjective or objective side effects of treatment were observed (data from Boon et al. 2007 [25])