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. 2009 Jul;19(7):1262–1269. doi: 10.1101/gr.090019.108

Figure 4.

Figure 4.

Comparison of Y2H results. (A) Area-proportional Venn diagram of PPIs found by 1-on-1, STD-1536, and STD-384 (generated by http://venndiagram.tk/). (B) Sensitivity (the percentage of core hits from each method in the whole core set) and (C) positive predictive value (PPV; the percentage of each method's hits that successfully pass pairwise retest and end up in core) of 1-on-1, STD-1536, and STD-384, restricted either to hub baits or to nonhub baits. (D) Sensitivity and (E) PPV of 1-on-1, STD-1536, STD-384, and Screen-Seq, restricting all data sets to the four nonhub and two hub baits screened in Screen-Seq. Error bars indicate standard error.