TABLE 3.

Global fit of SPR binding data

PS type	FXa binding	TFPI binding
Zn2+-containing	1.8 × 10−2/1.9 × 106 = 9.3 × 10−9	6.9 × 10−3/3.2 × 105 = 2.1 × 10−8
Zn2+-deficient	2.6 × 10−1/2.4 × 106 = 1.1 × 10−7	1.8 × 10−2/6.5 × 105 = 2.8 × 10−8

Calculated as k_off (s⁻¹)/k_on (M⁻¹s⁻¹) = K_d (M). Calculations were made from simultaneous fit of 5 or more sensograms using Biacore software.