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. 2009 Apr 20;53(7):3097–3099. doi: 10.1128/AAC.01552-08

TABLE 2.

Correlation of quinolone MICs with gyrA mutations for 105 Helicobacter pylori isolates

Agent gyrA mutation No. of isolates MIC range MIC50 MIC90
Sitafloxacin Asn87 14 0.03-0.5 0.25 0.5
Asp91 25 ≤0.015-0.25 0.12 0.25
Other 5 ≤0.015-0.12
None 61 ≤0.015-0.06 0.03 0.03
Garenoxacin Asn87 14 0.12-4 0.5 1
Asp91 25 0.12-2 0.5 1
Other 5 ≤0.015-0.5
None 61 ≤0.015-0.25 0.03 0.06
Levofloxacin Asn87 14 4-32 8 16
Asp91 25 2-8 4 8
Other 5 0.12-4
None 61 0.12-2 0.25 0.25