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. 2009 Apr 27;53(7):2865–2870. doi: 10.1128/AAC.00114-09

FIG. 3.

FIG. 3.

Transgenic mice were treated orally for 14 days with vehicle or with the indicated doses of adefovir dipivoxil (closed squares), HDP-(S)-HPMPA (closed triangles), 15M-HDP-(S)-HPMPA (open circles), or ODE-(S)-HPMPA (open diamonds). Adefovir dipivoxil-treated group had 3 to 5 animals per group, while the groups treated with HDP-(S)-HPMPA and 15M-HDP-(S)-HPMPA had 4 to 13 animals per group. The liver HBV DNA level was determined by Southern blot hybridization and is expressed as a percentage of the level for the untreated controls.