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. 2009 Apr 27;53(7):2865–2870. doi: 10.1128/AAC.00114-09

TABLE 3.

Uptake and conversion of [8-14C]-(S)-HPMPA and HDP-(S)-[8-14C]HPMPA to HPMPApp in HepG2 cells in vitro

Compound Amt taken up (pmol/flask)
(S)-HPMPA
HDP-(S)-HPMPA
24 h 48 h 24 h 48 h
UMa 33 27 596 255
HPMPA 62 70 402 344
HPMPAp 26 34 1007 888
HPMPApp 10 13 393 444
a

UM, unidentified metabolite.