FIG. 2.

Effect of lon-100 and sulA3 mutations on survival during treatment with nalidixic acid. Exponentially growing cultures were treated with the indicated concentrations of nalidixic acid for 180 min. The cells were then concentrated by centrifugation, resuspended in medium, diluted, and plated. (A) Lon deficiency. Open circles, wild-type strain DM4100; filled circles, lon-100 strain KD2372. (B) SulA deficiency. Open squares, sulA3 strain KD2510; filled squares, lon-100 sulA3 strain KD2377. Similar results were observed in three replicate experiments.