TABLE 1.
Demographic and clinical characteristics of the patients included in the study
| Variable | Value (mean ± SD or as indicated) |
|---|---|
| No. of patients (male/female) | 131 (86/45) |
| No. of EFV plasma concns analyzed | 375 |
| Ethnicity (Caucasian/black) | 129/2 |
| Age (yr) | 41.8 ± 9.1 |
| Weight (kg) | 64.9 ± 12.2 |
| Body mass index (kg2/cm) | 22.4 ± 3.4 |
| Daily dose (mg/day) | 597.2 ± 33.3 |
| EFV plasma concn (mg/liter) | 3.30 ± 2.05 |
| No. of plasma concns per patient | 2.9 ± 1.3 |
| Frequency (%) of indicated CYP2B6 | |
| polymorphism in patients genotypeda | |
| G/G | 53.1 |
| G/T | 28.1 |
| T/T | 18.8 |
a
Thirty-two of 131 patients (24.4%) were genotyped.