TABLE 2.

MICs of oxacillin for oxacillin-sensitive strain ATCC 29213 and MRSA strain WHO-2 in the presence and absence of anti-mecA PS-ODN833^a

Cultureb	Concn (μM) of PS-ODN833	MIC (μg/ml) of oxacillin
ATCC 29213 culture	0	0.5
Untreated WHO-2 control culture
WHO-2 cultures treated with:	0	1,024
L-PBS	0	1,024
F-PEI	0.2	1,024
L-M-ODN	18	1,024
F-ODN833	18	256
L-ODN833	0.7	16
	2	8
	6	2
	18	1

^aClassification of S. aureus strains by MIC of oxacillin: sensitive, MIC ≤ 2 μg/ml; resistant, MIC ≥ 4 μg/ml.

^bL-PBS, liposome-encapsulated PBS; F-PEI, free PEI; L-M-ODN, liposome-encapsulated mismatched PS-ODN; F-ODN833, free PS-ODN833; L-ODN833, liposome-encapsulated PS-ODN833.