FIG. 1.

SEVI enhances XMRV infections of human prostatic and nonprostatic cells. Effects of SEVI on XMRV RNA yields in DU145 cells (A to C), PrEC and PrSC cells (D), HFF and HeLa M cells (E), and all of these cell types (F) are shown. For comparison, PAP_247-282 and polybrene were used in panel A. Effects of SEVI, PAP_247-282, full-length PAP, PSA, and PSMA on XMRV infectivity are as indicated in panel B. Infections were with 1 TCID₅₀/10³ cells of XMRV for 3 days unless otherwise indicated. XMRV env RNA levels were determined by qRT-PCR. Data are average values ± standard deviations obtained from triplicate experiments (except for panel D).