Skip to main content
. 2009 May 6;83(14):7235–7243. doi: 10.1128/JVI.00452-09

FIG. 2.

FIG. 2.

Migration of cDC to the lung-draining LN (MLN) during primary RSV infections. (A) Mice were given CFSE intranasally 6 h before RSV or mock infection. Using flow cytometry, CFSE+ cDC subsets were identified in the MLN. (B) At several time points after RSV or mock infection, absolute numbers of CD11c+ cDC were determined in MLN and in RSV-infected mice in axillary LN (AxLN). (C) Lung-derived CFSE+/CD11c+ cDC were quantified per lung-draining LN and in axillary LN after RSV exposure or mock infection. (D) During primary RSV infection, absolute numbers of CD103+ cDC and CD11bhi cDC per MLN were determined. (E and F) Percentages (E) and absolute numbers (F) of lung-derived (CFSE+) CD103+ cDC and CD11bhi cDC per MLN during RSV infection were determined. The experiment was performed twice with five mice per time point. Average values of absolute cDC numbers per mouse MLN are depicted. Error bars represent the SEM (*, P < 0.05; **, P < 0.01; ns, not significant).