Primary structure of lantibiotics containing the mersacidin-lipid II binding motif (A) and the structure of the cell wall precursor lipid II (B). The binding motif of mersacidin and identical amino acids in the mersacidin-like lantibiotics are highlighted in gray. Dha, dehydroalanine; Dhb, dehydrobutyrine; Ala-S-Ala, lanthionine; Abu-S-Ala, methyllanthionine; DAla, d-alanine.