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. 2009 May 15;75(13):4580–4588. doi: 10.1128/AEM.00718-09

FIG. 2.

FIG. 2.

Overview of catabolic pathways encoded by the T. sibiricus genome. Substrates utilized are in bold, enzymes and proteins identified on the genome are in blue, and energy-rich intermediate compounds are in red. Panels: A, utilization of carbohydrates; B, utilization of proteins; C, utilization of lipids; D, glycolysis (modified EM pathway); E, pyruvate degradation; F, formation of proton motive force coupled with ATP generation. Abbreviations: POR, pyruvate:ferredoxin oxidoreductase; VOR, 2-ketoisovalerate:ferredoxin oxidoreductase; IOR, indolepyruvate:ferredoxin oxidoreductase; KGOR, 2-ketoglutarate:ferredoxin oxidoreductase; SCS, succinyl-CoA synthetase; ACS, acetyl-CoA synthetase; AOR, aldehyde:ferredoxin oxidoreductases; GLK, ADP-dependent glucokinase; PGI, phosphoglucose isomerase; GPI, glucose-6-phosphate isomerase; PFK, ADP-dependent phosphofructokinase; FBA, fructose-1,6-bisphosphate aldolase; TIM, triosephosphate isomerase; GAPOR, glyceraldehyde-3-phosphate:ferredoxin oxidoreductase; GAPN, nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase; PGM, phosphoglycerate mutase; PYK, pyruvate kinase; PGK, 3-phosphoglycerate kinase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; FBP, fructose-1,6-bisphosphatase; FDH, formate dehydrogenase; Fd(ox), oxidized ferredoxin; Fd(red), reduced ferredoxin; NSR, NADPH:S° oxidoreductase; CoASH, coenzyme A.