Table 2.
Immunization regimen | Proliferation SIa | Cytokine production (pg/ml)b |
||
IL-2 | IL-4 | IFN-γ | ||
Untreated | <20 | <20 | <20 | |
Control pcDNA3.1 | 1.2±0.2 | 40±11 | <20 | 156±35 |
pGRA4 | 4.0±0.3 | 125±23 | <20 | 1204±60 |
pGRA4/liposome | 9.8±0.8 | 168±10 | <20 | 1851±84 |
SI: stimulation index, expressed as the ratio between the mean counts per minute for triplicate stimulated cultures and the mean counts per minute for triplicate unstimulated cultures
The culture supernatants were examined for cytokine production
Values for IL-2, IL-4 are taken from 24 h of culturing, values for IFN-γ from 96 h of culturing