Table 1.
Trait | C3H.Apoe-/- (n) | C57BL/6J.Apoe-/- (n) | F2 Cross | |
---|---|---|---|---|
Lesion Size μm2 | Male | 149,936 ± 44,623 (8) | 168,478 ± 58,914 (4) | 82,818 ± 57,936 (49) |
Female | 118,281±13,623 (2) | 128,409 ± 37,964 (5) | 75,138 ± 59,169 (37) | |
Necrotic Core μm2 | Male | 63,766 ± 23,653 | 60,870 ± 25,644 | 23,129 ± 22,312 |
Female | 48,125 ± 12,128 | 41,136 ± 28,522 | 16,856 ± 16,878 | |
Chondrocyte-like Cell (% sections) | Male | 1 ±11 | 17 ± 39 | 6 ± 13 |
Female | 0 ± 0 | 0 ± 0 | 4±8 | |
Lateral Xanthomas (% sections) | Male | 18 ± 19 | 53±20 | 24±33 |
Female | 8 ± 11 | 21± 20 | 16±24 | |
Buried Fibrous Caps (% sections) | Male | 81 ± 40 | 52± 51 | 24±28 |
Female | 88 ± 34 | 48 ± 51 | 31±33 | |
Fibrous Cap Thickness (Average # of cells) | Male | 1.54 ± 0.81 | 2.5 ± 0.4 | 1.4±1.34 |
Female | 1.7 ± 0.47 | 1.54 ± 1.2 | 1.3 ±1.44 |
denotes P<0.05 All other differences are non-significant