Table 1.
α-adrenoceptor antagonists-induced apoptosis in human pancreatic cancer cells (mean ± SD)
Treatment |
TUNEL-positive cells (apoptotic index) (%) |
|||
PC-2 | PC-2 | PC-3 | PC-3 | |
100 μmol/L | 200 μmol/L | 100 μmol/L | 200 μmol/L | |
Yohimbine | 20.91 ± 2.43a | 39.41 ± 3.21a | 15.47 ± 2.19a | 21.22 ± 2.57a |
Urapidil | 1.57 ± 0.94 | 2.47 ± 1.03 | 1.98 ± 0.69 | 2.33 ± 0.92 |
Control | 2.56 ± 0.78 | 2.14 ± 0.62 |
P < 0.05 vs control.