Table 1.

Reported protein expression changes in SOD1^G93A model

Protein name	Accessiona	System	Change	Ref.
α Enolase	13637776	Mouse spinal cord	+	[71]
Aconitase 2	18079339	NSC34 mitochondria	+	[68]
Aldolase 1, A isoform	6671539	NSC34 mitochondria	+	[68]
Apolipoprotein E	6753102	Mouse spinal cord	+	[72]
Arginosuccinate synthase	114290	NSC34 cells	+	[73]
Calmodulin-dependent kinase 4 p64	50367	Mouse spinal cord	+	[50]
Casein kinase 1 delta p39	123289512	Mouse spinal cord	+	[50]
Cyclophilin A	118105	Mouse spinal cord	+	[71, 73]
Electron transfer flavoprotein α subunit	21759113	Mouse spinal cord	+	[71]
Enoyl-co a hydratase	62900285	Mouse spinal cord	+	[71]
Erp57	62868455	Rodent spinal cord	+	[37]
Extracellular regulated kinase 1 p42	52001483	Mouse spinal cord	+	[50]
Extracellular regulated kinase 3 p56	52001482	Mouse spinal cord	+	[50]
Ferritin heavy chain	120517	Mouse spinal cord	+	[71, 72]
Heat shock 27 kDa protein	547679	Mouse spinal cord	+	[72]
Heat shock protein 25 kDa	20342499	Mouse spinal cord	+	[72]
NADH dehydrogenase (ubiquinone) Fe-S protein 8	46195430	NSC34 mitochondria	+	[68]
NEDD8 conjugating enzyme Ubc12	46577656	Mouse spinal cord	+	[71]
P38 Hog MAP kinase p38	1346566	Mouse spinal cord	+	[50]
Peripherin	2253159	NSC34 mitochondria	+	[68]
Peroxiredoxin 1	547923	NSC34 cells	+	[73]
Peroxiredoxin 6	6671549	Mouse spinal cord	+	[72]
Phosphatidylinositol transfer protein alpha	21465804	Mouse spinal cord	+	[72]
Phosphoglycerate mutase 1	20178035	Mouse spinal cord	+	[71]
Protein disulfide isomerase	129729	Mouse spinal cord	+	[37, 71]
Protein kinase C delta p80	45330876	Mouse spinal cord	+	[50]
Protein kinase C mu p124	6679351	Mouse spinal cord	+	[50]
Pyrroline-5-carboxylate reductase I	13879494	NSC34 mitochondria	+	[68]
Pyruvate dehydrogenase E1	548409	Mouse spinal cord	+	[71]
Raf1 p73	62024525	Mouse spinal cord	+	[50]
Retinal pigment	30691136	NSC34 mitochondria	+	[68]
Sepiapterin reductase	2498952	Mouse spinal cord	+	[71]
Septin 5	83305642	NSC34 mitochondria	+	[68]
Similar to septin6 type II	26324430	NSC34 mitochondria	+	[68]
Superoxide dismutase mutant (k136e, c6a, c111s)	5822065	Mouse spinal cord	+	[72]
Translocase of inner mitochondrial membrane 50	22094989	NSC34 mitochondria	+	[68]
γ Actin	809561	NSC34 mitochondria	−	[68]
Aconitase 2	18079339	NSC34 mitochondria	−	[68]
Adenylate kinase 2	34328230	NSC34 mitochondria	−	[68]
ATP synthase, mitochondrial F1 complex, α subunit	6680748	NSC34 mitochondria	−	[68]
ATP synthase, mitochondrial F1 complex, β subunit	25052136	NSC34 mitochondria	−	[68]
ATPase β chain	20455479	Mouse spinal cord	−	[71]
Calmodulin-dependent kinase 4 p62		Mouse spinal cord	−	[50]
Chaperonin subunit 5 (ε)	6671702	NSC34 mitochondria	−	[68]
Chaperonin subunit 6A(ζ)	6753324	NSC34 mitochondria	−	[68]
Coiled-coil-helix-coiled-coil-helix domain	21313618	NSC34 mitochondria	−	[68]
Cytochrome c oxidase, subunit Va	21707954	NSC34 mitochondria	−	[68]
Dihydrolipoamide S-succinyl transferase	21313536	NSC34 mitochondria	−	[68]
Dihydropteridine reductase	62510641	Mouse spinal cord	−	[71]
DnaJ (Hsp 40) homolog subfamily B member 11	110625998	NSC34 mitochondria	−	[68]
Extracellular regulated kinase 6 p47	3023716	Mouse spinal cord	−	[50]
Glutamic pyruvate transaminase 2	21707978	NSC34 mitochondria	−	[68]
Glutathione S-transferase Mu 1	121716	NSC34 cells	−	[73]
Glutathione S-transferase Mu 2	121718	NSC34 cells	−	[73]
Glutathione S-transferase Mu 5	1346207	NSC 34 cells	−	[73]
Glutathione S-transferase Pi B	121747	NSC34 cells	−	[73]
Glycogen synthase kinase 3 alpha p45	134034134	Mouse spinal cord	−	[50]
Heat shock 70-kda protein 5	31981722	NSC34 mitochondria	−	[68]
Iron regulatory protein 1 (IRP 1)	46577686	Mouse spinal cord	−	[71]
Isocitrate dehydrogenase 3, β subunit	18700024	NSC34 mitochondria	−	[68]
(JNK;SAPK) beta p40	30578161	Mouse spinal cord	−	[50]
Mitochondrial ATP-dependent protease Lon	26984237	NSC34 mitochondria	−	[68]
Mitochondrial inner membrane protein (Mitofilin )	29427692	NSC34 mitochondria	−	[68]
NADH dehydrogenase (Ubiquinone) 1β subcomplex	58037109	NSC34 mitochondria	−	[68]
NADP-dependent leukotriene b4	73621182	NSC34 cells	−	[73]
NPC derived proline rich protein 1 (NDPP-1)	220500	NSC34 mitochondria	−	[68]
Ornithine aminotransferase	8393866	NSC34 mitochondria	−	[68]
Peroxiredoxin 3	6680690	NSC34 mitochondria	−	[68]
Phosphatidylinositol 3′-phosphatase p54	6679523	Mouse spinal cord	−	[50]
Profilin 1	51702779	Mouse spinal cord	−	[71]
Proteasome subunit beta type 8 precursor	1172603	NSC34 cells	−	[73]
Protein phosphatase 1-C subunit-gamma p30	1280027	Mouse spinal cord	−	[50]
Protein phosphatase 5-C subunit-p48	2407637	Mouse spinal cord	−	[50]
Pyruvate dehydrogenase E1α 1	6679261	NSC34 mitochondria	−	[68]
S6 kinase p70 (S6K) p83	54036143	Mouse spinal cord	−	[50]
Serine (or cysteine) proteinase inhibitor, clade B	114158675	Mouse spinal cord	−	[71]
Serine hydroxymethyl transferase2	21312298	NSC34 mitochondria	−	[68]
Stathmin	14625464	Mouse spinal cord	−	[72]
Stomatin-like protein 2	12963591	NSC34 mitochondria	−	[68]
Ts translation elongation factor, mitochondrial	21313468	NSC34 mitochondria	−	[68]
Tubulin α 2 chain	55977764	NSC34 mitochondria	−	[68]
Tubulin β 5	7106439	NSC34 mitochondria	−	[68]
Tyrosyl-t RNA synthetase	15488844	NSC34 mitochondria	−	[68]
Ubiquinol-cytochrome c reductase	13385168	NSC34 mitochondria	−	[68]
Voltage-dependent anion channel 1 (VDAC1)	6755963	NSC34 mitochondria	−	[68]
Voltage-dependent anion channel 2 (VDAC2)	6755965	NSC34 mitochondria	−	[68]

^aNCBI accession number.