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. Author manuscript; available in PMC: 2009 Jul 2.
Published in final edited form as: Tuberculosis (Edinb). 2007 Oct 24;88(1):1–6. doi: 10.1016/j.tube.2007.08.007

Figure 1. M. tuberculosis growth and normalized copy number of bacterial transcripts encoding antioxidant enzymes in infected mouse lung.

Figure 1

Panel A: M. tuberculosis growth and copy numbers of cytochrome bd oxidase (cydA) during infection. In lungs of C57BL/6 mice infected with M. tuberculosis H37Rv via the respiratory route, M. tuberculosis grew exponentially for about 20 days followed by chronic phase characterized with stabilization of bacterial counts (filled circles). Copy numbers of cydA transcripts were determined by real time RT-PCR and normalized against 16S rRNA (filled triangles, data from 27). Panels B–D: Copy numbers of bacterial transcripts encoding antioxidant enzymes. Normalized copy numbers of M. tuberculosis mRNAs against 16S rRNA were expressed as mean ± SD of data obtained from lungs of 3 or 4 mice per time point.