. Author manuscript; available in PMC: 2010 Mar 1.

Published in final edited form as: Vet Pathol. 2009 Mar;46(2):313–324. doi: 10.1354/vp.46-2-313

Table 1.

Distribution and severity of lesions in Gnptg^−/− and Gnptab^−/− mice.^*

	Gnptg^−/−		Gnptab^−/−
	14 Weeks	24 Months	14 Weeks	10 Months	WT
Pancreas	++	++++	++++	++++	−
Parotid Salivary Glands	++	++++	++++	++++	−
Steno Glands	+	+++	+++	++++	−
Maxillary Glands	++	+++	+++	++++
Submandibular Salivary Gland	+	++	+++	+++	−
Lacrimal Gland	−	++	+++	+++	−
Gastric Glands	−	−	++++	++++	−
Duodenal Glands	−	−	+	+	−
Bulbourethral Glands	++	++	++++	++++	−
Chondrocytes	−	−	++	++	−
Retina	−	−	+++	+++	−
Fibroblasts/Fibrocytes	−	−	−	−	−

Gnptg^−/− = γ-subunit deficient mice; Gnptab^−/− = α/β-subunit deficient mice; WT = wild-type; + = minimal; ++ = mild; +++ = moderate; ++++ = marked.