. Author manuscript; available in PMC: 2010 Mar 1.

Published in final edited form as: Vet Pathol. 2009 Mar;46(2):313–324. doi: 10.1354/vp.46-2-313

Table 3.

Man-6-P receptor affinity chromatography: binding of serum acid hydrolases to CI-MPR-affinity columns.^*

	% Enzyme bound to CI-MPR column
Enzymes	Controls (wild-type)	Gnptg^−/−	Gnptab^−/−
β-Hexosaminidase	26.7 ± 5.5	1.3 ± 0.7	0.25 ± 0.18
α-Mannosidase	30.6 ± 9.5	5.2 ± 1.6	0.11 ± 0.16
β-Mannosidase	31.0 ± 7.7	3.3 ± 1.9	0.79 ± 0.77
β-Galactosidase	51.8 ± 9.2	1.3 ± 0.6	0.56 ± 0.41
β-Glucuronidase	46.5 ± 7.6	41.6 ± 6.2	0.66 ± 0.43

Man-6-P = mannose 6-phosphate; CI-MPR = cation-independent Man-6-P receptor; Gnptg^−/− = γ-subunit deficient mice; Gnptab^−/− = α/β-subunit deficient mice.