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. Author manuscript; available in PMC: 2009 Jul 2.
Published in final edited form as: Mol Ther. 2008 Jan 8;16(3):466–473. doi: 10.1038/sj.mt.6300395

Figure 2.

Figure 2

Kinetics and biodistribution rAAV-mediated transduction via processed tendon allografts. Temporal bioluminescence images (BLI) of a representative mouse grafted with a freeze-dried FDL tendon allograft loaded with rAAV-Luc over 21 days show the localized biodistribution of rAAV-Luc transduction (heat map-yellow arrows) at the site of allograft implantation in the hind foot (a). Kinetics of in vivo rAAV transduction (b) based on average BLI signal intensity computed from measurements of total integrated light signal (photons emitted/cm2/sec) emitted from a standardized region of interest (ROI) in a standard 3 minute time interval (mean ± SEM; n=4).