Table 1.
Table 1 Category of Alerts and Types of Alerts Showing a Beneficial Effect on Prescribing and/or Clinical Outcome
| Category of Drug Alerts | Number of Alert Types | Number of Studies with Beneficial Effect on Prescribing | Number of Studies with No Effect on Prescribing | Number of Studies with Positive Effect on Clinical Outcomes |
|---|---|---|---|---|
| Basic drug alerts | ||||
| 1. Drug allergy warnings | 1 | 1 24 | — | — |
| 2. Drug–drug interactions | 1 | — | 1 24 | — |
| 3. Duplication alerts | 0 | — | — | — |
| 4. Basic medication order guidance | 2 | 2 24,28 | — | — |
| Advanced drug alerts | ||||
| 1. Drug-laboratory alerts | 4 | 4 26,27,31,36 | — | 1 31 |
| 2. Drug-condition alerts | ||||
| 2a Drug–disease contraindication | 0 | — | — | — |
| 2b appropriate prescribing | 4 | 2 17,28 | 2 18,19 | — |
| 2c drug-age alerts | 4 | 3 30,34,35 | 1 33 | 1 30 |
| 3. Drug-formulary alerts | 4 | 4 21,23,28,32 | — | 2 21,32 |
| 4. Dosing guidelines based on: | ||||
| 4a Renal Function | 2 | 2 29,31 | — | 1 29 |
| 4b age | 0 | — | — | — |
| 4c pregnancy/childbearing potential | 0 | — | — | — |
| 4d Pediatric patients/weight based dosing | 1 | 1 20 | — | — |
| 4e indications | 0 | — | — | — |
| Combination of basic and advanced features | 4 | 4 22,24,25,28 | — | — |
| Total | 27 | 23 | 4 | 5 |
Alert types showing beneficial effect on prescribing (second column), no effect on prescribing (third column) and positive effect on clinical outcomes (fourth column) compared to total number of alerts in a certain alert category (first column).