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. 2009 Jun;214(6):916–925. doi: 10.1111/j.1469-7580.2009.01080.x

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Journal compilation © 2009 Anatomical Society of Great Britain and Ireland

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Fig. 3 — Morphological changes in the proximal efferent ductules (EDs) of wild-type (WT) and estrogen receptor α knockout (αERKO) mice during postnatal development. (A) At low magnification, dilation of the ED lumen (arrow) in αERKO is notable from 10 days of age and is greatly expanded with age. Bar = 50 µm. (B) At high magnification, note a significant increase of epithelial height () in the WT mouse and significant decreases of epithelial () and nuclear () heights in the αERKO mouse with age. Bar = 10 µm. (C) Change of luminal diameter, (D) change of epithelial height and (E) change of nuclear height. Values represent mean ± S.D. Different letters indicate significant differences among experimental groups (P < 0.05).

Inline graphic — Morphological changes in the proximal efferent ductules (EDs) of wild-type (WT) and estrogen receptor α knockout (αERKO) mice during postnatal development. (A) At low magnification, dilation of the ED lumen (arrow) in αERKO is notable from 10 days of age and is greatly expanded with age. Bar = 50 µm. (B) At high magnification, note a significant increase of epithelial height () in the WT mouse and significant decreases of epithelial () and nuclear () heights in the αERKO mouse with age. Bar = 10 µm. (C) Change of luminal diameter, (D) change of epithelial height and (E) change of nuclear height. Values represent mean ± S.D. Different letters indicate significant differences among experimental groups (P < 0.05).