Fig. 6.

Shape variables (scaled linear distances) showing the greatest degree of difference between groups from EDMA. As explained in the figure, the color of the lines shows the direction of change. The variables shown here represent the upper and lower 10% of the sorted shape difference matrix; i.e. distances with the greatest group difference in either direction. Variables where this difference was statistically significant (P < 0.05) are represented by thicker lines. For each group comparison two views are included: a sagittal view of the left cerebral and cerebellar outer surface, and an internal mid-sagittal view of the left brain hemisphere. Note: the line connecting the temporal pole to the posterior corpus callosum in the first row (CL/P vs. Controls) is rendered semi-transparent to facilitate visualization.