Table 2.
Method | Normalization | AUC |
SHEBA | None | 0.941 |
QP tableau search | norm2 | 0.925 |
QP tableau search | norm1 | 0.904 |
QP tableau search | norm3 | 0.904 |
VAST | None | 0.890 |
TableauSearch | norm2 | 0.871 |
TOPS | None | 0.871 |
TableauSearch | norm1 | 0.869 |
QP tableau search | None | 0.854 |
TableauSearch | None | 0.846 |
TableauSearch | norm3 | 0.832 |
Area under ROC curve (AUC) for the 200 query set against the ASTRAL SCOP 95% sequence identity non-redundant database consisting of 15273 domains, for different methods and normalizations. Note that only the tableau search methods (our method (QP tableau search) and TableauSearch) require normalization, as VAST, SHEBA and TOPS report normalized scores themselves and so do not require an external normalization step to combine results for different queries. The table is ordered by decreasing AUC.