Fig. 6.

Dicer and Dicer-regulated miRs expressed in primary human GBM tissues are inversely associated with ICAM-1 expression. Representative examples of Dicer/ICAM-1 expression by immunohistochemistry and miR expression by in situ hybridization. Expression of Dicer, miRs and ICAM-1 was graded as follows: grade 0, negative staining; +1, weakly positive staining; +2, moderately positive staining; +3, strongly positive at focal areas; +4, strongly and diffusely positive throughout the lesion. Original magnification was ×20.