Figure 1.
Growth inhibitory effects of tannic acid and chemotherapeutic agents. Mz-ChA-1, CC-LP-1 and TFK-1 human cholangiocarcinoma cells were incubated with 50 μM tannic acid (TA), 5-fluorouracil (5FU), gemcitabine (GEM), mitomycin C (MMC) or their respective control diluents. Proliferation was assessed after 72 hours, and the proliferation index calculated. Growth inhibition by tannic acid was similar to that of the chemotherapeutic agents. The data represents mean and 95% confidence intervals from 3-5 separate studies.