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. 2009 Jul 7;15(25):3134–3141. doi: 10.3748/wjg.15.3134

Table 3.

Effect of surgical interventions on serum bile acids and conjugates in CD cohorts (nmol/L)

BA class BA/BA-conjugate Control No surgery Ileocecal resection Colectomy Other surgery Ileocecal resection + other surgery
Primary CA 62.5 52.0 160.0ab 71.0 57.5c 89.0b
TCA 23.6 0.0a 0.0ab 9.5c 8.0c 0.0
GCA 383.5 240.5a 156.0ab 375.0c 212.0 221.5a
CDCA 196.5 144.0a 505.0ab 174.5 153.0 121.0
TCDCA 230.5 81.0a 19.0ab 37.5ab 55.5a 17.0ab
GCDCA 1446.0 848.5a 767.0a 1059.0 663.5a 772.0
Secondary DCA 239.8 90.5a 11.0a 6.5ab 17.5a 53.0d
TDCA 48.2 5.9a 0.0ab 0.0a 0.0ab 0.0a
GDCA 238.6 64.0a 0.0ab 0.0ab 0.0ab 43.5a
LCA 15.0 7.0a 5.9a 3.0a 4.7a 2.9a
TLCA 0.0 0.0 0.0ab 0.0ab 0.0 0.0
GLCA1 17.4 3.6a 0.0a 0.0 2.3 0.0
UDCA 28.5 14.5a 26.0b 12.7 53.5 22.5
TUDCA 0.0 0.0 0.0a 0.0a 0.0a 0.0a
GUDCA1 137.9 95.2a 59.7 92.1 323.5 75.6
Tertiary HDCA 0.0 27.0a 10.0a 9.5a 9.0a 2.0a
THDCA 0.0 0.0a 0.0 0.0 0.0 0.0
GHDCA1 0.0 0.0 0.0 0.0 2.0 0.0

Control: n = 310; No surgery: n = 64, n = 311; Ileocecal resection: n = 41, n = 161; Colectomy: n = 22, n = 81; Other surgery: n = 12, n = 41; Ileocecal resection + other surgery: n = 12, n = 91. Data expressed as medians.

a

P < 0.05 vs control,

b

P < 0.05 vs no surgery,

c

P < 0.05 vs ileocecal resection,

d

P < 0.05 vs colectomy (Mann-Whitney U test).