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. Author manuscript; available in PMC: 2009 Jul 4.
Published in final edited form as: J Urol. 2008 Mar 18;179(5):1850–1856. doi: 10.1016/j.juro.2008.01.047

Table 1. Significant Associations Between Urine Markers and Biopsy Findings in Untreated IC Patients.

Cystoscopic criteria required Criteria not required
Biopsy Urine n* r** 95% CI P value n* r** 95% CI P value
HB-EGF in urothelium IL-8 22 -0.30 -0.51, -0.10 0.005 34 -0.34 -0.55, -0.12 0.002
EGF receptor in urothelium cGMP 22 0.35 0.13, 0.57 0.002 35 0.34 0.13, 0.55 0.002
EGF receptor in urothelium IL-6 30 0.29 0.02, 0.57 0.04 45 0.29 0.07, 0.51 0.01
Mast cells in lamina propria IL-8 22 0.13 -0.18, 0.45 0.40 34 0.29 0.06, 0.52 0.01
*

some values are missing, due to loss or insufficiency of the relevant urine aliquot or slide.

**

Kendall's tau-b correlation coefficient