Table 1. Significant Associations Between Urine Markers and Biopsy Findings in Untreated IC Patients.
Cystoscopic criteria required | Criteria not required | ||||||||
---|---|---|---|---|---|---|---|---|---|
Biopsy | Urine | n* | r** | 95% CI | P value | n* | r** | 95% CI | P value |
HB-EGF in urothelium | IL-8 | 22 | -0.30 | -0.51, -0.10 | 0.005 | 34 | -0.34 | -0.55, -0.12 | 0.002 |
EGF receptor in urothelium | cGMP | 22 | 0.35 | 0.13, 0.57 | 0.002 | 35 | 0.34 | 0.13, 0.55 | 0.002 |
EGF receptor in urothelium | IL-6 | 30 | 0.29 | 0.02, 0.57 | 0.04 | 45 | 0.29 | 0.07, 0.51 | 0.01 |
Mast cells in lamina propria | IL-8 | 22 | 0.13 | -0.18, 0.45 | 0.40 | 34 | 0.29 | 0.06, 0.52 | 0.01 |
some values are missing, due to loss or insufficiency of the relevant urine aliquot or slide.
Kendall's tau-b correlation coefficient