Table 2.
Patient characteristics by Treatment group
| Characteristics | SHM N=166 | AHM N=166 | p value |
|---|---|---|---|
| Male sex [N (%)] | 44 (26.51) | 55 (33.10) | 0.23** |
| Age in years [Mean ± SD] | 54.9 ± 13.88 | 55.6 ± 13.07 | 0.60** |
| Aneurysm Characteristics | |||
| Anterior Aneurysm Location [N (%)] | 103 (62.05) | 104 (62.65) | 1.00** |
| Number of Aneurysm [Median (25%,75%] | 1 (1,2) | 1 (1,2) | 0.29 |
| Aneurysm Size (mm) [Median (25%,75%] | 8 (5,10) | 7 (4,9) | 0.09** |
| Patient Presentation | |||
| Sentinel Headache [N (%)] | 19 (11.44) | 22 (13.25) | 0.74 |
| Seizure at onset [N (%)] | 11(6.63) | 21 (12.65) | 0.09** |
| Loss of consciousness [N (%)] | 87 (52.40) | 70 (42.16) | 0.08** |
| Prehospital worsening [N (%)] | 33 (19.88) | 43 (25.90) | 0.24 |
| History of Hypertension [N (%)] | 63 (40.12) | 87 (52.72) | 0.03** |
| History of Diabetes [N (%)] | 5 (3.18) | 17 (8.48) | 0.06** |
| History of stroke [N (%)] | 16 (10.30) | 13 (7.87) | 0.56 |
| History of CAD [N (%)] | 19 (12.17) | 10 (6.06) | 0.08** |
| Hunt and Hess Grade | |||
| Hunt and Hess 1 [N (%)] | 28 (16.87) | 26 (15.66) | 0.88 |
| Hunt and Hess 2 [N (%)] | 12 (7.23) | 32 (19.28) | 0.00 |
| Hunt and Hess 3 [N (%)] | 61 (36.75) | 44 (26.51) | 0.06 |
| Hunt and Hess 4 [N (%)] | 52 (31.33) | 47 (28.31) | 0.63 |
| Hunt and Hess 5 [N (%)] | 13 (7.83) | 17 (10.24) | 0.57 |
| Poor Hunt and Hess grade [N (%)] | 65 (39.10) | 64 (38.50) | 1.00** |
| Admission Lab/Imaging: | |||
| CT sign of edema [N (%)] | 46 (27.70) | 43 (25.90) | 0.80 |
| CT sign of infarction [N (%)] | 3 (1.80) | 12 (7.20) | 0.03** |
| CT sign of ICH [N (%)] | 37 (22.20) | 36 (21.60) | 0.89 |
| CT sign of IVH [N (%)] | 128 (77.10) | 134 (80.70) | 0.50 |
| CT sign of hydrocephalus [N (%)] | 133 (80.10) | 131 (78.90) | 0.89 |
| CT sign of MLS [N (%)] | 30 (18.07) | 25 (15.00) | 0.56 |
| Fisher Group: | |||
| Fisher Group 1 [N (%)] | 0 (0) | 1 (0.60) | 1.00 |
| Fisher Group 2 [N (%)] | 11 (6.63) | 13 (7.83) | 0.83 |
| Fisher Group 3 [N (%)] | 137 (82.53) | 142 (85.54) | 0.55 |
| Fisher Group 4 [N (%)] | 18 (10.84) | 10 (6.02) | 0.17 |
| Poor Fisher Group [N (%)] | 137 (82.53) | 142 (85.50) | 0.55** |
| Admission glucose [Mean ± SD] | 168.7±46.60 | 171.2±58.40 | 0.98** |
**
included in multivariate logistic regression analysis
Note: p values were computed using Fisher exact test, t-test or Wilcoxon 2-sample test where appropriate
Legend: SHM – Standard Hyperglycemia Management; AHM – Aggressive Hyperglycemia Management; CAD – Coronary Artery Disease; ICH – Intracerebral hemorrhage; IVH – intraventricular hemorrhage; MLS – midline shift