Table 2.
Examples of anti-RSV drugs.
Compound | Company | Structure | Indication | Stage of development |
Mechanism of action |
|
---|---|---|---|---|---|---|
MBX-300 | Microbiotix (USA) |
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Infection | Discontinued | G protein inhibitor |
|
VP-14637 | ViroPharma (USA) |
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Infection | Discontinued | F protein inhibitor |
|
RSV-604 | Arrow Therapeutics (Novartis, UK) |
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Phase II clinical trial |
N protein inhibitor |
||
RFI-641 | Wyeth (USA) |
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Infection, prophylaxis prophylaxis |
Discontinued | F protein inhibitor |
|
LY-2 53963 | Eli Lilly (USA) |
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Infection | Discontinued | Unspecified | |
EICAR | Asahi Kasei Pharma |
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Infection | Discontinued | L-polymerase inhibitor | |
BMS-433771 | Bristol-Myers Squibb |
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Infection | Discontinued | F protein inhibitor |
|
ALN-RSV01 | Alnylam (USA) |
RNA | Infection, prophylaxis |
Phase II clinical trial |
Gene expression inhibitor |
RSV: Respiratory syncytial virus