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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Ultrasound Med Biol. 2009 Feb 5;35(5):839–846. doi: 10.1016/j.ultrasmedbio.2008.11.009

Figure 1.

Figure 1

Schematic representing setup for corneal speed-of-sound determinations. The cornea rests face downwards on a rubber ring. The time of flight of the ultrasound pulse to the cornea, t1, across the cornea (t2 − t1) and to a flat glass surface underlying the cornea, t3, are determined. By measuring the time-of-flight to the glass surface on either side of the cornea (t0′ and t0″), we can interpolate the time-of-flight to the glass surface at any position beneath the cornea, had the cornea not been present. Corneal speed-of-sound can then be determined from the trans-corneal time-of-flight and the shift between the interpolated and observed positions of the underlying glass surface plus the known speed-of-sound of the immersion medium.