. Author manuscript; available in PMC: 2009 Jul 6.

Published in final edited form as: Eur J Pharmacol. 2007 Nov 12;580(1-2):161–168. doi: 10.1016/j.ejphar.2007.07.071

Table 2.

Declining phase properties of the MK-801 induced hyperlocomotion peak in the young and aged mice

	MK-801 (mg/kg)	0.015	0.05	0.15	0.3
Declining time to half-peak height (min)	young	84.2±8.0	74.6±5.7	122.2±6.9	177.6±4.2
	aged	95.8±7.2	125.2±8.1^a	161.5±7.2^a	257.5±5.9^a
Half-peak height/half-peak declining duration	young	5.4±1.6	7.0±1.0	9.7±0.9	8.3±0.9
	aged	3.5±1.2	3.8±0.9^a	5.2±0.4^a	5.1±1.1^a

Declining time to half-peak height is the duration from the MK-801 induced hyperlocomotion peak to when the locomotion declines by 50%. Half-peak height/half-peak declining duration is the ratio of half-peak height over declining time to half-peak height. Results are expressed as mean ± S.E.M.

P < 0.05, significantly different from the young mice.