Table 3.
MK-801 (mg/kg) | 0 | 0.015 | 0.05 | 0.15 | 0.3 | 0.6 | 1 | |
---|---|---|---|---|---|---|---|---|
Time for stereotypy to decline to 50% (min) | Young | 0 | 0 | 0 | 24.8±5.2 | 39.3±3.2 | 97.1±4.9 | 123.3±5.9 |
aged | 0 | 0 | 0 | 33.7±4.1 | 96.8±3.7a | 120.0±5.8a | 206.2±10.1a |
Stereotypy half-peak area is the area for the top half of the stereotypy peak.
P < 0.05, significantly different from the young mice.