Table 1.

Allele and Genotype Frequencies of SNPs in Pedigrees

SNP	Sample	Allele Distribution		Genotype Distribution			TDT
		G	A	GG	AG	AA	t(G)/t(A)	χ2	p
rs2254298	Parents	196	32	83	30	1	---	---	---
	Autistic probands	104	10	47	10	0	21/9	4.80	0.03
rs53576	Parents	166	62	61	44	9	---	---
	Autistic probands	84	30	30	24	3	23/21	0.09	0.76

SNP, single nucleotide polymorphism; TDT, transmission disequilibrium test; t(G)/t(A), number of transmitted G and A alleles from heterozygous parents