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. Author manuscript; available in PMC: 2009 Jul 6.
Published in final edited form as: Pharmacol Biochem Behav. 2006 Oct 18;85(2):385–392. doi: 10.1016/j.pbb.2006.09.006

Figure 5.

Figure 5

Percentage of cocaine-lever responding (upper panel) and overall rate of responding (lower panel) in subjects administered either cocaine alone (n=9, filled circles) or cocaine following a pretreatment with 10 mg/kg of pregnanolone (n=5, grey diamonds), or 0.32 mg/kg of lorazepam (n=6, unfilled diamonds). Cocaine was administered i.p. immediately before the start of the session and pregnanolone and lorazepam were administered i.p. 5 minutes before the start of the session Percentages of cocaine-lever responding and response rates are expressed as mean ± S.E.M. The shaded area on the bottom panel represents the mean response rate following saline administration ± 20 %.