. Author manuscript; available in PMC: 2009 Jul 6.

Published in final edited form as: Pharmacol Biochem Behav. 2006 Oct 18;85(2):385–392. doi: 10.1016/j.pbb.2006.09.006

Table 3.

ED₅₀ values and their 95% CI for the percentage of cocaine-lever responding produced by cocaine administered alone, or cocaine following a pretreatment with 10 mg/kg of pregnanolone or 0.32 mg/kg of lorazepam.

	216	297	444	473	442	474	331	299	443	Mean
Control	1.414	2.398	2.936	2.503	2.979					2.446
95% CI										1.662–3.23
Pregnanolone	2.05	7.83	3.61	11.87	5.53	ND	ND	ND	ND	6.177*

Control				2.503	2.979	3.573	3.522	2.504	2.504	2.931
95% CI										2.394–3.468
Lorazepam	ND	ND	ND	2.504	7.8	3.037	5.288	2.504	0.8959	3.661*

The asterisk represents an ED₅₀ value that falls outside of the control confidence interval.