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. Author manuscript; available in PMC: 2009 Jul 6.
Published in final edited form as: Exp Cell Res. 2007 May 24;313(14):3057–3065. doi: 10.1016/j.yexcr.2007.05.018

Figure 3.

Figure 3

Figure 3

Figure 3

Effect of knocking down CTCF mRNA on UV irradiation-induced cell death. (A) Effect of knocking down CTCF mRNA on CTCF expression in HCE cells. (B) Effect of knocking down CTCF mRNA on UV irradiation-induced caspase 3 activation in HCE cells. (C) Effect of knocking down CTCF mRNA on viability of UV irradiation-induced HCE cells. (D) Effect of knocking down CTCF mRNA on CTCF mRNA and protein expression in ML-1 cells. (E) Effect of knocking down CTCF on UV irradiation-induced caspase 3 activation in ML-1 cells. (F) Effect of knocking down CTCF mRNA on viability of UV irradiation-induced ML-1 cells. HCE and ML-1 cells were transfected with non-specific siRNA (for the controls) or CTCF-specific siRNA for 3 days before performing experiments. Caspase 3 activity and cell viability were determined by using Western analysis and MTT assay, respectively. Symbols “*’ represent the statistical significance (n=6, p<0.05) between control and siRNA transfected cells in the presence and absence of UV irradiation, respectively.