Table 1.

Characteristics of the 36 chimpanzees that comprised the study population

Animal no.	Sex	Age (y)	Heart weight (g)	Body weight (kg)	Heart weight: body weight ratio	Clinical finding	Myocardial fibrosisa	Hypertension	Myocarditis	VPCs
1	M	33	463	60.5	0.0076	SCD	+++	yes	+	yes
2	M	23	550	74.5	0.0075	SCD	+++	no	+	yes
3	M	22	635	72.0	0.0088	SCD	+++	no	+	yes
4	M	29	490	57.0	0.0085	SCD	+++	no	WNL	yes
5	M	28	420	57.0	0.0074	SCD	++	no	+	yes
6	M	21	650	94.5	0.0069	SCD	+	no	WNL	yes
7	M	19	500	74.5	0.0067	SCD	+	no	+	yes
8	M	32	315	42.5	0.0074	Septicemia	++	no	WNL	no
9	M	39	350	40.5	0.0086	Hyperadrenocortism	+++	no	++	no
10	M	27	530	74.0	0.0071	Neoplasia	++	no	++	yes
11	M	36	355	76.0	0.0046	Thromboembolism	++	no	++	yes
12	M	13	450	70.0	0.0064	Septicemia	+	no	WNL	no
13	M	25	660	62.0	0.0106	SCD	+++	yes	+	yes
14	M	32	430	42.5	0.0101	Anesthetic reaction	++	no	+	no
15	M	16	n/a	52.0	n/a	Septicemia	WNL	no	+++	no
16	M	35	495	61.0	0.0081	SCD	+++	no	WNL	no
17	M	28	355	56.5	0.0063	SCD	++	no	WNL	yes
18	M	40	325	61.9	0.0053	SCD	+++	no	WNL	yes
19	M	13	n/a	28.4	n/a	Renal failure	WNL	no	WNL	no
20	M	22	290	54.5	0.0053	Trauma	++	no	WNL	no
21	M	10	340	57.0	0.0059	Trauma	WNL	no	WNL	no
22	M	20	340	56.5	0.0060	Trauma	++	no	+	no
23	M	24	275	55.5	0.0049	Thromboembolism	++	no	WNL	no
24	M	30	n/a	47.4	n/a	Renal failure	WNL	no	WNL	yes
25	M	32	n/a	68.0	n/a	Renal failure	++	no	+	yes
26	F	25	360	49.3	0.0073	Renal failure	++	no	++	no
27	F	18	330	50.7	0.0065	Renal failure	WNL	no	+++	no
28	F	16	415	44.0	0.0094	Renal failure	++	no	WNL	no
29	F	13	195	43.0	0.0045	Neoplasia	+	no	WNL	no
30	F	17	285	61.7	0.0046	SCD	+	no	WNL	yes
31	F	21	375	84.5	0.0044	SCD	+++	no	WNL	yes
32	F	19	250	64.0	0.0039	Renal failure	n/a	n/a	n/a	no
33	F	29	340	39.0	0.0087	Renal failure	+	no	WNL	yes
34	F	31	263.5	59.0	0.0045	Cerebral infarction	WNL	no	WNL	no
35	F	18	250	37.0	0.0067	Renal failure	++	no	WNL	no
36	F	22	450	95.0	0.0047	Anesthetic reaction	+++	yes	WNL	no

F, female; M, male; n/a, not available; SCD, sudden cardiac death; WNL, within normal limits

^a+, minimal; ++, mild; +++, moderate

^b+, structural heart disease with or without myocardial fibrosis; ++, no structural heart disease and no myocardial fibrosis; +++, no structural heart disease with myocardial fibrosis