Block diagram representing the various stages in the serial cascaded systems analysis performed in this paper for prototype PVD#4. The x-ray spectrum (Boone and Seibert 1997) used in the calculations corresponds to that used in our measurements and is characterized by a fluence of = 262,410 × rays/mm2/mR. The HgI2 photoconductor is described by a quantum efficiency = 0.643 with a variance of 0.229. It is also described by a photoconductive gain represented by = 11,246 (mean number of electron-hole pairs generated in the photoconductor per interacting x ray) with a variance of 9.86×106 - as determined via EGS4 Monte Carlo simulations (El-Mohri et al 2007) assuming a thickness of 210 μm for HgI2, a density of 5.72 g/cm3 and an internal ionization energy of 4.2 eV.(Schieber et al, 1997; Alexiev et al, 2004) The stochastic spatial spreading is characterized by T3 obtained from the empirically determined MTF divided by the sine function for a square pixel aperture of 127 μm. The gain = 0.392 with a variance of 0.238 corresponds to the collection efficiency of charges created in the photoconductor. The value of was obtained by fitting the calculated x-ray sensitivity to the empirically determined value, with taken as a free parameter. The array pixels are characterized by a spatial spreading represented by the aforementioned sine function, T5, and an additional stage (labeled apix) representing the sampling of the signal. The additive noise of the electronic acquisition system is characterized by σADD, which was empirically determined from dark NPS measurements to be ~2000 e (rms). Note that, for simplicity, k-fluorescent interactions have not been separated as a parallel branch in the model since their effect on the MTF, as determined from Monte Carlo simulations that include such interactions, was found to be negligible.