Table 1.
Activities |
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Crude Venom Localities | LD50 (mg/kg) | MHD (μg/mouse) | Hemolytic (mm2/μg) | Coagulant (Human Plasma) IU thrombin- like/mg | Fibrinolytic (Fibrin Plate- Pg+ mm2/μg) |
Riverside 1 | 2.5 | 8.1 ± 1.3 | 24.4 ± 3.7 | 7.0 ± 0.1 | 1. 4 ± 0.3 |
Riverside 2 | 0.6 | No Hemorrhage | 13.3 ± 0.1 | 3.8 ± 0.1 | 0 |
San Bernardino 1 | 0.7 | No Hemorrhage | 16.5 ± 1.9 | 12.2 ± 0.2 | 0 |
San Bernardino 2 | 3.0 | 2.8 ± 0.5 | 22.6 ± 2.8 | 0 | 1.6 ± 0.1 |
San Bernardino 3 | 5.7 | 2.5 ± 0.8 | 14.3 ± 2.1 | < 1.0 | 6.7 ± 0.2 |
LD50 = The amount of venom protein that will kill 50% of a mouse population.
MHD = Minimal hemorrhagic dose; the minimal amount of venom protein that will produced a 10 mm hemorrhagic spot.
Hemolytic = Indirect activity.
Pg+ = Fibrinogen containing plasminogen.