. Author manuscript; available in PMC: 2010 Apr 1.

Published in final edited form as: Comp Biochem Physiol C Toxicol Pharmacol. 2008 Sep 5;149(3):307–316. doi: 10.1016/j.cbpc.2008.08.007

Table 1.

Comparison of activities of C. o. helleri venoms from 5 geographical locations.

	Activities
Crude Venom Localities	LD₅₀ (mg/kg)	MHD (μg/mouse)	Hemolytic (mm²/μg)	Coagulant (Human Plasma) IU thrombin- like/mg	Fibrinolytic (Fibrin Plate- Pg+ mm²/μg)
Riverside 1	2.5	8.1 ± 1.3	24.4 ± 3.7	7.0 ± 0.1	1. 4 ± 0.3
Riverside 2	0.6	No Hemorrhage	13.3 ± 0.1	3.8 ± 0.1	0
San Bernardino 1	0.7	No Hemorrhage	16.5 ± 1.9	12.2 ± 0.2	0
San Bernardino 2	3.0	2.8 ± 0.5	22.6 ± 2.8	0	1.6 ± 0.1
San Bernardino 3	5.7	2.5 ± 0.8	14.3 ± 2.1	< 1.0	6.7 ± 0.2

LD₅₀ = The amount of venom protein that will kill 50% of a mouse population.

MHD = Minimal hemorrhagic dose; the minimal amount of venom protein that will produced a 10 mm hemorrhagic spot.

Hemolytic = Indirect activity.

Pg⁺ = Fibrinogen containing plasminogen.