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. 2009 Jun 17;5:31. doi: 10.1186/1744-8069-5-31

Figure 5.

Figure 5

Capsaicin or resiniferatoxin induces ROS production in cultured mouse DRG neurons through TRPV1 activation. (A) Capsaicin significantly increases ROS production and capsazepine blocks capsaicin induced ROS production (30 minutes: ##P < 0.01 compared to capsaicin). (B) Resiniferatoxin significantly increases ROS production and resiniferatoxin blocks capsaicin induced ROS production (30 minutes: ###P < 0.001 compared to resiniferatoxin). (C) There is no change in ROS production in DRG neurons from TRPV1 deficient mice after capsaicin or resiniferatoxin stimulation.