Table 1.

Increased prevalence of psychiatric disorders among persons with MS compared to the general population

Disorder	Prevalence in MS	Prevalence in general population
Major depressive disorder, 12-month	15.7% [33]	7.4% [33]
Major depressive disorder, lifetime	22.8% [40]	16.2% [97]
Any anxiety disorder, lifetime	36% [10, 62]	25% [63]
Generalized anxiety disorder	18.6% [10, 62]	3.0% [98]
Bipolar disorder, lifetime	0.3% [72]	0.2% [99]
Alcohol abuse, lifetime	13.6% [77]	7.4% [100]
Substance misuse, past month	18.7% [78]	11.1% [100]