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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Biol Psychiatry. 2009 Apr 15;66(3):259–266. doi: 10.1016/j.biopsych.2009.02.012

Table 2.

Plasma Concentrations of Citalopram and Prolactin

Citalopram Concentrations (ng/mL) Mean ± Standard Deviation
Controls Depressed Older Adults
End of Infusion (EOI) 87.8 ± 51.9 76.2 ± 33.5
15 minutes Post-EOI 56.4 ± 12.0 52.5 ± 14.2
30 minutes Post-EOI 52.2 ± 15.8 51.1 ± 13.3
60 minutes Post-EOI 48.3 ± 10.9 46.2 ± 13.5
90 minutes Post-EOI 46.3 ± 8.4 42.5 ± 10.5
120 minutes Post-EOI 43.9 ± 11.4 44.1 ± 13.1
Prolactin Concentrations (ng/mL) Mean ± Standard Deviation
Controls Depressed Older Adults
Placebo Citalopram %Δ Placebo Citalopram %Δ
Pre-Infusion 8.1 ± 3.2 9.0 ± 4.6 6.0 ± 25.5 7.1 ± 2.4 7.8 ± 3.0 13.1 ± 50.1
End of Infusion (EOI) 9.5 ± 4.6 16.3 ± 14.9 69.5 ± 142.0 7.4 ± 4.2 12.4 ± 7.6 47.3 ± 68.8
15 minutes Post-EOI 9.1 ± 3.8 14.8 ± 13.7 59.8 ± 116.8 7.3 ± 3.7 11.5 ± 7.8 25.3 ± 52.9
30 minutes Post-EOI 9.3 ± 3.9 15.6 ± 10.6 81.5 ± 125.3 6.9 ± 2.8 11.1 ± 6.1 39.8 ± 75.3
60 minutes Post-EOI 8.7 ± 3.7 14.8 ± 8.5 81.5 ± 105.0 6.2 ± 2.1 10.5 ± 5.2 52.5 ± 77.2
90 minutes Post-EOI 9.5 ± 4.4 14.1 ± 6.9 58.6 ± 64.0 6.6 ± 2.8 10.3 ± 4.6 50.6 ± 62.8
120 minutes Post-EOI 10.5 ± 4.7 13.3 ± 6.3 31.5 ± 37.4 7.0 ± 2.6 11.3 ± 6.8 43.9 ± 47.9