Table 1.
Number of human genes | Number of bovine genes | |
---|---|---|
Human TRAV subgroup | ||
HuTRAV1 | 2 | 1 |
HuTRAV2 | 1 | 6 + 1Ψ |
HuTRAV3 | 1 | 6 + 1Ψ |
HuTRAV4 | 1 | 3 + 2Ψ |
HuTRAV5 | 1 | 6 |
HuTRAV6 | 1 | – |
HuTRAV7 | 1 | – |
HuTRAV8 | 6 + 1Ψ | 7 + 7Ψ |
HuTRAV9 | 2 | 13 + 5Ψ |
HuTRAV10 | 1 | 4 |
HuTRAV11 | 1Ψ | 3 |
HuTRAV12 | 3 | – |
HuTRAV13 | 2 | 10 + 5Ψ |
HuTRAV14/DV4 | 1 | 8 + 3Ψ |
HuTRAV15 | 1Ψ | – |
HuTRAV16 | 1 | 3 |
HuTRAV17 | 1 | 2 + 3Ψ |
HuTRAV18 | 1 | 7 + 1Ψ |
HuTRAV19 | 1 | 4 + 1Ψ |
HuTRAV20 | 1 | 4 |
HuTRAV21 | 1 | 5 |
HuTRAV22 | 1 | 28 + 4Ψ + 1a |
HuTRAV23 | 1 | 8 + 17Ψ |
HuTRAV24 | 1 | 5 + 6Ψ |
HuTRAV25 | 1 | 17 + 5Ψ +1a |
HuTRAV26 | 2 | 29 + 5Ψ |
HuTRAV27 | 1 | 1 |
HuTRAV28 | 1Ψ | 4 |
HuTRAV29/DV5 | 1 | 4 |
HuTRAV30 | 1 | – |
HuTRAV31 | 1Ψ | – |
HuTRAV32 | 1Ψ | – |
HuTRAV33 | 1Ψ | – |
HuTRAV34 | 1 | – |
HuTRAV35 | 1 | 1 |
HuTRAV36/DV7 | 1 | 1 + 2Ψ |
HuTRAV37 | 1Ψ | – |
HuTRAV38/DV6b | 2 | 6 |
HuTRAV39 | 1 | 2 |
HuTRAV40 | 1 | – |
HuTRAV41 | 1 | |
Human TRDV subgroup | ||
HuTRDV1c | 1 | 93 + 9Ψ +2a |
HuTRDV2 | 1 | – |
HuTRDV3d | 1 | 1 |
Bovine TRDV subgroup | ||
BoTRDV1c | 1 | 93 + 9Ψ +2a |
BoTRDV2 | – | 3 |
BoTRDV3 | – | 2 + 1a |
BoTRDV4d | 1 | 1 |
New bovine subgroup | ||
Gene 50 subgroup | – | 23 + 1Ψ |
Gene 54 subgroup | – | 9 + 1a |
Gene 57 subgroup | – | 2Ψ |
Gene 82 subgroup | – | 6 |
Gene 96 subgroup | – | 2Ψ |
Gene 196 subgroup | – | 1Ψ |
Gene 259 subgroup | – | 1a |
Gene 284 subgroup | – | 1a |
Gene 327 subgroup | – | 1 |
Gene 356 subgroup | – | 1Ψ |
Gene 385 subgroup | – | 1Ψ |
Total number of V genes in TRAV/DV locus | 57 | 430 |
The interspecies subgroups were named after the human subgroup, and the novel bovine subgroups (subgroups without human members) were named after the member with the lowest number. The total number of bovine and human genes in each subgroup is listed, as well as the total number of V genes in the locus
Ψ pseudogene
aIncomplete sequence
bThis subgroup consists of one TRAV and one TRAV/DV
cBovine TRDV1 and human TRDV1 subgroups can be considered to form one interspecies subgroup because human TRDV1 is >75% identical to multiple bovine TRDV1 genes. However, this does not hold for all bovine TRDV1 genes
dHuman TRDV3 is homologous to bovine TRDV4 and form an interspecies subgroup based on >75% identity at the nucleotide level