Table 1.
Comaprison of carrier frequency of KIR genes in four Iranian populations
| KIR | Persian(Per) | Bakhtiari (Bak) | Arab (Arb) | Azeri (Aze) | p values | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| n = 248 | n = 96 | n = 76 | n = 84 | Per vs. Bak | Per vs. Arb | Per vs. Aze | Bak vs. Arb | Bak vs. Aze | Arb vs. Aze | |
| %F (N) | %F (N) | %F (N) | %F (N) | |||||||
| A haplotype associated KIR genes | ||||||||||
| 2DL1 | 98.0 (244) | 94.8 (91) | 100 (76) | 98.0 (83) | ||||||
| 2DL3 | 91.0 (226) | 89.6 (86) | 89.5 (68) | 89.2 (75) | ||||||
| 3DL1 | 94.0 (238) | 95.8 (92) | 85.5 (65) | 90.5 (76) | ||||||
| 2DS4 | 96.0 (239) | 97.9 (94) | 98.7 (75) | 98.8 (83) | ||||||
| B haplotype associated KIR genes | ||||||||||
| 2DL2 | 56.8 (141) | 54.1 (52) | 63.1 (48) | 67.9 (57) | ||||||
| 2DL5 | 58.0 (144) | 54.1 (52) | 67.1 (51) | 73.8 (62) | 0.013 | 0.0083 | ||||
| 3DS1 | 33.0 (83) | 45.8 (44) | 42.1 (32) | 38.0 (32) | 0.035 | |||||
| 2DS1 | 35.0 (89) | 42.7 (41) | 44.7 (34) | 39.2 (33) | ||||||
| 2DS2 | 54.0 (135) | 49.0 (47) | 56.3 (49) | 70.2 (59) | 0.015 | 0.046 | 0.0041 | |||
| 2DS3 | 38.3 (95) | 27.1 (26) | 50.0 (38) | 53.5 (45) | 0.015 | 0.0025 | 0.0004 | |||
| 2DS5 | 25.4 (63) | 39.6 (38) | 35.5 (27) | 34.5 (29) | 0.012 | |||||
| Framework genes/pseudogenes | ||||||||||
| 2DL4 | 100 (248) | 100 (96) | 100 (76) | 100 (84) | ||||||
| 3DL2 | 100 (248) | 100 (96) | 100 (76) | 100 (84) | ||||||
| 3DL3 | 100 (248) | 100 (96) | 100 (76) | 100 (84) | ||||||
| 2DP1 | 98.0 (243) | 96.9 (93) | 98.7 (75) | 100 (84) | ||||||
| 3DP1 | 100 (248) | 100 (96) | 100 (76) | 100 (84) | ||||||
Frequency (%F) of carriers of each gene is expressed as a percentage and defined as the number of individuals carrying the gene (N) divided by the number of individuals studied (n) in the given population group. The p values are given only for those pairwise comparisons indicating significant (<0.05) differences