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. Author manuscript; available in PMC: 2009 Jul 7.
Published in final edited form as: Exp Hematol. 2007 Apr;35(4 Suppl 1):78–86. doi: 10.1016/j.exphem.2007.01.028

Figure 4.

Figure 4

Wild type littermate control (WT), but not IL-31 R -/- CFU-GM are responsive in vitro to the synergistic proliferative effects of GM-CSF or Il-3 with the combinations of either SCF or FL. Concentrations of Cytokine used: GM-CSF or IL-3 (10ng/ml), SCF (50ng/ml), FL (100ng/ml). Results are shown as mean +/- 1 SEM for CFU-GM derived colonies (expressed per 5×104 bone marrow cells plated) for 7 different mice in each group from a total of 2 separate experiments. Significance: a p<0.001 for colonies formed in the presence of GM-CSF or IL-3 plus SCF or FL compared to that of the additive colonies formed in plates of GM-CSF alone plus SCF or FL alone, and of IL-3 alone plus SCF or FL alone.