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. Author manuscript; available in PMC: 2009 Dec 25.

Published in final edited form as: J Med Chem. 2008 Dec 25;51(24):8019–8026. doi: 10.1021/jm8011867

Circular dichroism spectra of oxidized human MAO-B, mofegiline inhibited MAO-B, and of known MAO-B flavin N(5) adducts. Oxidized MAO-B (), After inhibition by mofegiline (), the MAO-B N(5) flavin adduct formed after inhibition by pargyline (), and the MAO-B N(5) flavin adduct formed after inhibition by phenylethylhydrazine (). All spectral data were acquired in 50 mM potassium phosphate, pH 7.5 containing 0.8% (w/v) β-D-octylglucoside.

Inline graphic — Circular dichroism spectra of oxidized human MAO-B, mofegiline inhibited MAO-B, and of known MAO-B flavin N(5) adducts. Oxidized MAO-B (), After inhibition by mofegiline (), the MAO-B N(5) flavin adduct formed after inhibition by pargyline (), and the MAO-B N(5) flavin adduct formed after inhibition by phenylethylhydrazine (). All spectral data were acquired in 50 mM potassium phosphate, pH 7.5 containing 0.8% (w/v) β-D-octylglucoside.